Systematic Review

The search methodology is a critical step in the systematic review process. A systematic review (SR) must demonstrate that sufficient effort has been made to identify as many methodologically sound studies as possible to answer a clinical question.

MUHC Librarians will:

  • translate your question into a comprehensive search strategy,
  • conduct the literature search,
  • identify relevant grey literature,
  • deliver the results using EndNote,
  • provide you with a documented methodology report and PRISMA flow chart.

To request support for your systematic review, we ask that you first complete the MUHC Libraries’ Work Plan for a Systematic Review of the Literature and send it to a hospital librarian.

Upon receipt of the work plan, the librarian and lead investigator will meet to discuss the project and sign a Memorandum of Understanding, in order to establish a time frame for delivery of results, as well as to ensure that both parties understand their mutual responsibilities in the project.

If you have never conducted a systematic review, give us a call. Your hospital librarian will arrange a meeting to review the process, requirements and answer any questions you may have.

If you are considering undertaking a systematic review, MUHC librarians have compiled a list of essential resources which you may find useful.

MUHC librarians have supported several projects since launching our systematic review service in 2012. Examples of recently published systematic reviews supported by MUHC librarians:

Butler-Laporte, G., Smyth, E., Amar-Zifkin, A., Cheng, M. P., McDonald, E. G., Lee, T. C.(2020). Low-Dose TMP-SMX in the Treatment of Pneumocystis jirovecii Pneumonia: A Systematic Review and Meta-analysis. Open forum infectious diseases, 7(5) ofaa112.

El-Kefraoui, C., Olleik, G., Chay, M.A., Kouyoumdjian, A., Nguyen-Powanda, P., Rajabiyazdi, F., Do, U., Derksen, A., Landry, T., Amar-Zifkin, A., Ramanakumar, A.V., Martel, M., Baldini, G., Feldman, L., Fiore, J.F. Jr (2020). Opioid versus opioid-free analgesia after surgical discharge: protocol for a systematic review and meta-analysis. BMJ open, 10(1) e035443.

Valanci-Aroesty, S., Alhassan, N., Feldman, L.S., Landry, T., Mastropietro, V., Fiore, J.Jr, Lee, L., Fried, G.M., Mueller, C.L. (2020). Implementation and Effectiveness of Coaching for Surgeons in Practice – A Mixed Studies Systematic Review. Journal of surgical education, [epub ahead of print].

Beaudoin, P.L., Anchouche, S., Gaffar, R., Guadagno, E., Ayad, T., Poenaru, D. (2020). Barriers in access to care for patients with head and neck cancer in resource-limited settings: a systematic review. JAMA otolaryngology- head & neck surgery, [epub ahead of print].

Meng, F., Zuo, K.J., Amar-Zifkin, A., Baird, R., Cugno, S., Poenaru, D. (2019). Pediatric burn contractures in low- and lower middle-income countries: a systematic review of causes and factors affecting outcome. Burns: journal of the International Society for Burn Injuries, [epub ahead of print].

Kaur, A., Mackin, S.T., Schlosser, K., Wong, F.L., Elharram, M., Delles, C., Stewart, D.J., Dayan, N., Landry, T., Pilote, L. (2019). Systematic review of microRNA biomarkers in acute coronary syndrome and stable coronary artery disease. Cardiovascular research, 116(6) 1113-1124.

Fiore, J.F. Jr, Olleik, G., El-Kefraoui, C., Verdolin, B., Kouyoumdjian, A., Alldrit, A., Figueiredo, A.G., Valanci, S., Marquez-GdeV, J.A., Schulz, M., Moldoveanu, D., Nguyen-Powanda, P., Best, G., Banks, A., Landry, T., Pecorelli, N., Baldini, G., Feldman, L.S. (2019). Preventing opioid prescription after major surgery: a scoping review of the literature on opioid-free analgesia. British journal of anaesthesia, 123(5) 627-636.

Juźwik, C.A., Drake, S.S., Zhang, Y., Paradis-Isler N., Sylvester, A., Amar-Zifkin, A., Douglas, C., Morquette, B., Moore, C.S., Fournier, A. (2019). microRNA dysregulation in neurodegenerative diseases: A systematic review. Progress in neurobiology, 182 101664.

Garfinkle, R., Savage, P., Boutros, M., Landry, T., Reynier, P., Morin, N., Vasilevsky, C.A., Filion, K.B. (2019). Incidence and predictors of postoperative ileus after loop ileostomy closure: a systematic review and meta-analysis. Surgical endoscopy, 33(8) 2430-2443.

Sandal, S., Dendukuri, N., Wang, S., Guadagno, E., Ekmekjian, T., Alam, A. (2019). Efficacy of educational interventions in improving measures of living donor kidney transplantation activity: a systematic review and meta-analysis. Transplantation, 103(12) 2566-2575.

Toobaie, A., Yousef, Y., Balvardi, S., St-Louis, E., Baird, R., Guadagno, E., Poenaru, D. (2019). Incidence and prevalence of congenital anomalies in low- and middle-income countries: A systematic review. Journal of pediatric surgery, 54(5) 1089-1093.

Drudi, L.M., Tat, J., Ades, M., Mata, J., Landry, T., MacKenzie, K.S., Steinmetz, O.K., Gill, H.L. (2019). Preoperative Exercise Rehabilitation in Cardiac and Vascular Interventions. Journal of surgical research, 237 3-11.

Bilgic, E., Al Mahroos, M., Landry, T., Fried, G.M., Vassiliou, M.C., Feldman, L.S. (2019). Assessment of surgical performance of laparoscopic benign hiatal surgery: a systematic review. Surgical endoscopy, 33(11) 3798-3805.

Connors, N.J., Alsakha, A., Larocque, A., Hoffman, R.S., Landry, T., Gosselin, S. (2019). Antipsychotics for the treatment of sympathomimetic toxicity: A systematic review. American journal of emergency medicine, 37(10) 1880-1890.

Yousef, Y., St-Louis, E., Baird, R., Smith, E.R.,, Guadagno, E., St-Vil, D., Poenaru, D. (2019). A systematic review of capacity assessment tools in pediatric surgery: Global Assessment in Pediatric Surgery (GAPS) Phase I. Journal of pediatric surgery, 54(4) 831-837.

MacDonald, K., Krishnan, A., Cervenka, E., Hu, G., Guadagno, E., Trakadis, Y. (2018). Biomarkers for major depressive and bipolar disorders using metabolomics: A systematic review. American journal of medical genetics. Part B, Neuropsychiatric genetics, 180(2) 122-137.

St-Louis, E., Paradis, T., Landry, T., Poenaru, D. (2018). Factors contributing to successful trauma registry implementation in low- and middle-income countries: A systematic review. Injury, 49(12) 2100-2110.

Li, C., Wang, A., Wang, C., Ramamurthy, J., Zhang, E., Guadagno, E., Trakadis, Y. (2018). Metabolomics in patients with psychosis: A systematic review. American journal of medical genetics. Part B, Neuropsychiatric genetics, 177(6) 580-588.

Elharram, M., Dayan, N., Kaur, A., Landry, T., Pilote, L. (2018). Long-Term Cognitive Impairment After Preeclampsia: A Systematic Review and Meta-analysis. Obstetrics and gynecology, 132(2) 355-364.

Groleau, C., Morin, S.N., Vautour, L., Amar-Zifkin, A., Bessissow, A. (2018). Perioperative corticosteroid administration: a systematic review and descriptive analysis. Perioperative medicine (London, England), 7:10.

Shapiro, A.J., Davis, S.D., Polineni, D., Manion, M., Rosenfeld, M., Dell, S.D., Chilvers, M.A., Ferkol, T.W., Zariwala, M.A., Sagel, S.D., Josephson, M., Morgan, L., Yilmaz, O., Olivier, K.N., Milla, C., Pittman, J.E., Daniels, M.L.A., Jones, M.H., Janahi, I.A., Ware, S.M., Daniel, S.J., Cooper, M.L., Nogee, L.M., Anton, B., Eastvold, T., Ehrne, L., Guadagno, E., Knowles, M.R., Leigh, M.W., Lavergne, V.; American Thoracic Society Assembly on Pediatrics. (2018). Diagnosis of Primary Ciliary Dyskinesia. An Official American Thoracic Society Clinical Practice Guideline. American journal of respiratory and critical care medicine, 197(12) e24-e39.

St-Louis, E., Oosenbrug, M., Landry, T., Baird, R. (2018). Enrollment and reporting practices in pediatric general surgical randomized clinical trials: A systematic review and observational analysis. Journal of pediatric surgery, 53(5) 879-884.

St-Louis, E., Safa, N., Guadagno, E., Baird, R. (2018). Gastrocutaneous fistulae in children – A systematic review and meta-analysis of epidemiology and treatment options. Journal of pediatric surgery, 53(5) 946-958.

Paradis, T., St-Louis, E., Landry, T., Poenaru, D. (2018). Strategies for successful trauma registry implementation in low- and middle-income countries-protocol for a systematic review. Systematic reviews, 7(1) 33.

Alyahya, B., Friesen, M., Nauche, B., Laliberté, M. (2018). Acute lamotrigine overdose: a systematic review of published adult and pediatric cases. Clinical toxicology (Philadelphia, Pa.), 56(2) 81-89.

Fiore, J.F. Jr, Figueiredo, S., Balvardi, S., Lee, L., Nauche, B., Landry, T., Mayo, N.E., Feldman, L.S. (2018). How Do We Value Postoperative Recovery?: A Systematic Review of the Measurement Properties of Patient-reported Outcomes After Abdominal Surgery. Annals of surgery, 267(4) 659-669.

Karimian, N., Niculiseanu, P., Amar-Zifkin, A., Carli, F., Feldman, L.S. (2018). Association of Elevated Pre-operative Hemoglobin A1c and Post-operative Complications in Non-diabetic Patients: A Systematic Review. World journal of surgery, 42(1) 61-72.

Garant, A., Guilbault, C., Ekmekjian, T., Greenwald, Z., Murgoi, P., Vuong, T. (2017). Concomitant use of corticosteroids and immune checkpoint inhibitors in patients with hematologic or solid neoplasms: A systematic review. Critical reviews in oncology/hematology, 120 86-92.

Shapiro, A.J., Josephson, M., Rosenfeld, M., Yilmaz, O., Davis, S.D., Polineni, D., Guadagno, E., Leigh, M.W., Lavergne, V. (2017). Accuracy of Nasal Nitric Oxide Measurement as a Diagnostic Test for Primary Ciliary Dyskinesia: A Systematic Review and Meta-Analysis. Annals of the American Thoracic Society, 14(7) 1184-1196.

Gorgui, J., Gasbarrino, K., Georgakis, M.K., Karalexi, M.A., Nauche, B., Petridou, E.T., Daskalopoulou, S.S. (2017). Markers of Vascular Dysfunction After Hypertensive Disorders of Pregnancy: A Systematic Review and Meta-Analysis. Metabolism: clinical and experimental, 69, 51-66.

Grand’Maison, S., Pilote, L., Okano, M., Landry, T., Dayan, N. (2016). Markers of Vascular Dysfunction After Hypertensive Disorders of Pregnancy: A Systematic Review and Meta-Analysis. Hypertension, 68(6), 1447-1458.

Maertens, H., Madani, H., Landry, T., Vermassen, F., Van Herzeele, I., Aggarwal, R. (2016). Systematic review of e-learning for surgical training. The British Journal of Surgery, 103(11), 1428-1437.

Gasbarrino, K., Gorgui, J., Nauche, B., Côté, R., Daskalopoulou, S.S. (2016). Circulating adiponectin and carotid intima-media thickness: A systematic review and meta-analysis. Metabolism: clinical and experimental, 65(7), 968-986.

Ortega-Deballon, I., Hornby, L., Shemie, S.D., Bhanji, F., Guadagno, E. (2016). Extracorporeal resuscitation for refractory out-of-hospital cardiac arrest in adults: A systematic review of international practices and outcomes. Resuscitation, 101, 12-20.

Fitzcharles, M.A., Ste-Marie, P.A., Häuser, W., Clauw, D.J., Jamal, S., Karsh, J., Landry, T., LeClercq, S., McDougall, J.J., Shir, Y., Shojania, K., Walsh, Z. (2016). Efficacy, tolerability and safety of cannabinoid treatments in the rheumatic diseases: A systematic review of randomized controlled trials. Arthritis Care & Research, 68(5), 681-688.

Fiore, J.F. Jr, Bejjani, J., Conrad, K., Niculiseanu, P., Landry, T., Lee, L., Ferri, L.E., Feldman, L.S. (2016). Systematic review of the influence of enhanced recovery pathways in elective lung resection. The Journal of Thoracic and Cardiovascular Surgery, 151(3), 708-715.

Click here to access the list of systematic reviews published before 2016.